股骨骨促结缔组织增生性纤维瘤的影像学特征

Imaging features of desmoplastic fibroma of the femur bone

目的探讨股骨骨促结缔组织增生性纤维瘤(DFB)的影像学特征。方法回顾分析经病理证实的10例股骨DFB患者的影像学资料。结果 X线平片显示,股骨干骺端见偏心性或中心性类圆形或梭形透亮影,病灶长轴沿股骨的长轴走向。CT可见股骨干骺端局部软组织肿块,邻近骨皮质缺损,骨质向内凹陷,边缘稍硬化,病灶内可见点状钙化。MRI表现为肿瘤在T1WI、T2WI均呈低信号。结论 DFB具有侵袭性特征,手术时需要较大的切除范围;其影像特征与非骨化纤维瘤等相似,易导致误诊,鉴别诊断有重要临床价值。

Objective To investigate the imaging features of desmoplastic fibroma of bone（DFB） on the femur.Methods Imaging data of 10 patients with pathologically proved DFB of the femur were analyzed retrospectively.Results Round or spindle-shaped eccentric or central translucent shadows were showed in distal femoral metaphysics,the long axis of lesions was along that of the femurs in plain X-ray films.CT showed local soft-tissue mass around the lesions,adjacent cortical bone defect with peripheral cortical attenuation and punctate calcifications.The zone of transition between tumor and normal bone was slightly hardened.MRI showed low signals on T2WI and T1WI.Conclusion DFB is a rare tumor with strong local aggressiveness.A wide surgical resection and careful long-term follow-up are necessary.Differential diagnosis from other soft tissue lesions presenting as bony erosion and benign fibrous lesions,especially from non-ossifying fibroma and fibrous dysplasia has important clinical significance of DFB.