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CpG ODN生物学活性和免疫作用的研究进展 被引量:6

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摘要 CpG ODN为人工合成的含胞嘧啶和鸟嘌呤二核苷酸的寡聚脱氧核苷酸,能与Toll样受体9(TLR9)结合而发挥作用。CpG ODN能直接或间接激活树突状细胞、单核细胞和巨噬细胞以及B淋巴细胞、NK细胞、T淋巴细胞等,使之分泌许多生物活性因子和细胞因子,从而在感染性疾病和肿瘤的免疫治疗中发挥重要作用。
机构地区 三峡大学医学院
出处 《现代免疫学》 CAS CSCD 北大核心 2011年第2期168-171,共4页 Current Immunology
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参考文献20

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二级参考文献22

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