缬沙坦治疗糖尿病合并高血压的疗效观察

Effect Observation of Valsartan Treatment for Hypertensive Patients with Diabetes

目的探讨缬沙坦治疗糖尿病合并高血压的疗效和安全性。方法选择76名糖尿病合并高血压患者，在维持糖尿病治疗的情况下，给予缬沙坦治疗，观察血压（收缩压SBP和舒张压DBP）、空腹血糖（FBG）、餐后2h血糖（2h—PBG）、糖化血红蛋白（HbAlc）、空腹胰岛素（INS）等的变化。结果76名糖尿病合并高血压患者经过缬沙坦的治疗，血压、空腹血糖、餐后2h血糖、糖化血红蛋白和空腹胰岛素均有明显的降低，治疗前后具有显著性差异。结论缬沙坦治疗糖尿病合并高血压疗效确切，副作用小，值得临床进一步推广应用。

Objective To investigate the effects of Valsartan in the hypertensive patients with diabetes. Methods 76 hypertensive patients with diabetes were treated by Valsartan for 14 weeks. Systolic and diastotic blood pressure （SBP, DBP）, Blood Glucose, HbAlc, INS before and after treatment were examined. Results Compared to each other before and after treatment with Valsartan, SBP, DBP, FBG, 2h-PBG, HbAlc and INS were significantly decreased. Conclusion Valsartan can improve the hypertensive patients with diabetes effectively and is worthy of further application.