摘要
在诊治营养不良和超重体力劳动者的临床实践中,发现营养不良可引起肿瘤。因而有针对性的对一些肿物(包括颌下腺囊肿和腋窝囊肿等)单独注射硫胺素(维生素B1)。发现疗效很好,本文对1例溶骨性骨肉瘤注射硫胺素,经围绕癌瘤一次注射硫胺素300 mg后,癌块急剧缩小50%以上。国际上对硫胺素是否致癌或治癌尚有争议,本文以临床实践为依据,提出硫胺素缺乏可能是骨肉癌的病因之一。
Based on therapeutic effect of intra-cystic thiamin for submandibular gland cyst and Baker's cyst,subcutaneous thiamin was injected around the malignancy in a case with osteolytic osteosarcoma at her right humerus after fracture.Biopsy and thiamin infusion were encouraged by three conspicuous clinical features in the case: suffering from prolonged severe malnutrition,mild injury causing fracture and triggering malignancy exactly at the site of the wound.The authentic pathologic diagnosis was "osteo-malignancy".It should be further categorized as osteolytic osteosarcoma because of its rapid course,absence of new bone,and the absorption of bony fragments.Within two days after peri-mass infusion of thiamin 300 mg,the tumor mass drastically reduced over 50% in volume.Thereby,thiamin deficiency might be one of the etiology of osteosarcoma.
出处
《南通大学学报(医学版)》
2011年第2期92-93,共2页
Journal of Nantong University(Medical sciences)
基金
国家自然科学基金资助项目(30971117)
关键词
骨肉瘤
硫胺素
营养缺乏病
osteosarcoma
thiamin
deficiency disease