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血清电解质紊乱与肝硬化及其并发症的相关性研究 被引量:3

Serum Electrolyte Disorder in Liver Cirrhosis and Its Complications:A Correlation Study
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摘要 目的探讨电解质紊乱与肝硬化及其并发症、预后的关系,为临床提供理论依据。方法回顾分析我院2004年6月~2009年3月收治的132例肝硬化合并电解质紊乱患者的并发症和预后。结果三种离子紊乱依次是低Na+>低Cl->低K+,其中Na+、Cl-变化具有统计学意义,离子紊乱以低Na+低Cl-最多见。随着血钠水平的降低,肝性脑病、肝肾综合征、顽固性腹水的发生率明显上升,低血钠被纠正,好转率升高。结论肝硬化后电解质紊乱,尤其低钠血症,血钠越低并发症的发生率越高,死亡率也越高。及时纠正电解质紊乱有利于临床症状的改善。 Objective To explore the relationship among the serum electrolyte disorder in liver cirrhosis and its complications and diagnosis,so as to provide a theory basis for clinical practice. Methods We analyzed the clinical data of 132 cases of complications and diagnosis with hepatocirrhosis amalgamating electrolyte disorder treated from June 2004 to March 2009 in our hospital retrospectively. Results The sequences of electrolyte disturbances were hyponatrem,ahypochloremia,and hypokalemia,among which the level changes of serum sodium and serum chlorine with there was statistical significance,and hyponatremia and hypochloremia were often seen in the patients.With the decreases of serum sodium levels,the incidence rate of hepatic encephalopathyn and hepatorenal syndrome and refractory ascites all rised obviously. As the hyponatrem was remitted,the improvement rate increased distinctly. Conclusion In the patients with hepatocirrhosis amalgamating electrolyte disorder,the lower of the serum sodium level,the higher of the rate of cirrhosis complication,the higher of the mortality rate. So it is beneficial to improve clinical symptoms totimely correction of electrolyte disorder
作者 王青
出处 《中国现代医生》 2011年第11期62-63,共2页 China Modern Doctor
关键词 肝硬化 电解质紊乱 并发症 Liver cirrhosis Electrolyte disorder Complications
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  • 1刘海涛,毛艳,许清华,唐国彬.肝硬化腹水患者低钠血症的诊治现状[J].中华临床医师杂志(电子版),2011,5(20):6079-6081. 被引量:4
  • 2王蔚文.临床疾病诊断与疗效判断标准[M].北京:科学技术文献出版社,2010:125.
  • 3Forman LM, Lueey MR. Predicting the prognosis of chronic liver disease:an evolution from child to meld mayo end- stage liver disease[ J]. Hepatology,2001 ;33:473-475.
  • 4Bernardi M, Laffi G, Salvagnini M, et al. Effcacy and safety of the stepped care medical treatment of ascites in liver cirrhosis: a randomized controlled clinical trial comparing two diets with different sodium content [J]. Liver, 1993 ;13 : 156-162.
  • 5Abramham A. Jacob CK. Severe hypanatraemia current concepts on pathogenesis and treatment[J]. Natl Med India,2001 ; 14 : 277.
  • 6Franz CC,Egger S,Born C,et al.Potential drug-drug interactions and adverse drug reactions in patients with liver cirrhosis[J].Eur J Clin Pharmacol,2012,68(2):179-188.
  • 7Corpechot C,Carrat F,Poujol-Robert A,et al.Noninvasive elastography-based assessment of liver fibrosis progression and prognosis in primary biliary cirrhosis[J].Hepatology,2012,56(1):198-208.
  • 8Liu JZ,Almarri MA,Gaffney DJ,et al.Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis[J].Nat Genet,2012,44(10):1137-1141.
  • 9Teltschik Z,Wiest R,Beisner J,et al.Intestinal bacterial translocation in rats with cirrhosis is related to compromised paneth cell antimicrobial host defense[J].Hepatology,2012,55(4):1154-1163.
  • 10张薇薇,袁学华,谭华炳,朱琳,占国清,杜卫星,李儒贵.肝硬化失代偿期低钠血症与病重程度的关系[J].临床消化病杂志,2009,21(5):296-298. 被引量:9

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