摘要
脓毒性脑病(SE)是由脓毒症导致的急性、弥散性、可逆性脑损伤,患者存在短期的意识或认知功能障碍,有时发生记忆和行为缺陷,其发病率在脓毒症患者中为9%~71%,是严重创(烧)伤后脓毒症的常见并发症之一。
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2011年第2期128-130,共3页
Chinese Journal of Burns
基金
国家自然科学基金(30872683、30973120)
参考文献14
-
1Takao Kumazawa, Masahiro Hotta, Shinichi Sugiyama. A New Hot-line Diagnositic Method for XLPE Power Cables--AC Superposition Method [A]. Proceedings of the IEEE International Conference on Properties and Applications of Dielectric Materials[C], Seoul Kore
-
2Wratten ML. Therapeutic approaches to reduce systemic inflammation in septic-associated neurologic complications. Eur J Anaesthesiol Suppl, 2008,42 : 1-7.
-
3Siami S, Annane D, Sharshar T. The encephalopathy in sepsis. Crit Care Clin, 2008,24( 1 ) :67-82 ,viii.
-
4Goverman J. Autoimmune T cell responses in the central nervous system. Nat Rev Immunol, 2009,9(6) :393-407.
-
5Appel SH, Beers DR, Henkel JS. T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening? Trends Immunol, 2010,31 ( 1 ) :7-17.
-
6Audoy-Remus J, Richard JF, Soulet D, et al. Rod-shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2. J Neurosci, 2008,28(41 ) :10187-10199.
-
7Handa O, Stephen J, Cepinskas G. Role of endothelial nitric oxide synthase-derived nitric oxide in activation and dysfunction of cerebrovascular endothelial cells during early onsets of sepsis. Am J Physiol Heart Circ Physiol, 2008,295 ( 4 ) : H 1712-1719.
-
8Yong VW, Rivest S. Taking advantage of the systemic immune system to cure brain diseases. Neuron, 2009,6d( 1 ) :55-60.
-
9D'Mello C, Le T, Swain MG. Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factor alpha signaling during peripheral organ inflammation. J Neurosci, 2009, 29 (7) :2089-2102.
-
10Benoit M, Desnues B, Mege JL. Macrophage polarization in bacterial infections. J Immunol, 2008, 1 81 ( 6 ) : 3733-3739.
同被引文献29
-
1姚咏明,盛志勇,黄立峰.The Effect of a Novel Cytokine,High Mobility Group Box 1 Protein,on the Development of Traumatic Sepsis[J].Chinese Journal of Integrative Medicine,2009,15(1):13-15. 被引量:21
-
2卢中秋,梁欢,李景荣,邱俏檬,周铁丽,章圣辉,胡国新,吴斌.头孢哌酮钠联合左氧氟沙星治疗对大鼠创伤弧菌脓毒症血中mCD14的影响[J].中国急救医学,2006,26(8):602-604. 被引量:9
-
3Wratten ML. Therapeutic approaches to reduce systemic inflamma- tion in septic-associated neurologic complications [ J ]. Eur J Anaesthesiol Suppl, 2008, 42: 1-7.
-
4Sprung CL, Peduzzi PN, Shatney CH, et al. Impact of encephalopathy on mortality in the sepsis syndrome. The Veterans Administration Systemic Sepsis Cooperative Study Group [ J]. Crit Care Med, 1990 , 18 (8) : 801-806.
-
5Chen MK, Guilarte TR. Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair [ J]. Pharmacol Ther, 2008, 118 (1): 1-17.
-
6Hong GL, Lu CJ, Lu ZQ, et al. Surgical treatment of 19 cases with vibrio necrotizing fasciitis [J]. Bums, 2012, 38 (2) : 290-295.
-
7Sharshar T, Annane D, de la Grandmaison GL, et al. The neuropathology of septic shock [ J ]. Brain Pathol, 2004, 14 (1) : 21-33.
-
8Zhang Z, Chopp M, Powers C. Temporal profile of microglial response following transient ( 2 h) middle cerebral artery occlusion [J]. Brain Res, 1997, 744 (2): 189-198.
-
9Casellas P, Galiegue S, Basile AS. Peripheral benzodiazepine receptors and mitochondrial function[ J]. Neuroehem Int, 2002, 40 (6): 475-486.
-
10Papadopoulos V, Leeanu L. Translocator protein (18 kDa ) TSPO : an emerging therapeutic target in neurotrauma [ J ]. Exp Neurol, 2009, 219 (1): 53-57.
引证文献3
-
1洪广亮,戴晓琴,向兰,卢中秋,赵光举,吴斌,李萌芳,张纯武.创伤弧菌脓毒症大鼠脑组织转位蛋白的表达及抗菌药物的干预[J].中华急诊医学杂志,2013,22(3):260-265. 被引量:1
-
2李俊聪,董宁,祝筱梅,张庆红,姚咏明.高迁移率族蛋白B1上调PC12细胞α7型乙酰胆碱受体表达的研究[J].中国急救复苏与灾害医学杂志,2013(6):526-529. 被引量:2
-
3邢燕,程东良,史长松.安宫牛黄丸对小儿严重脓毒症体外膜肺氧合脑损伤的脑保护作用[J].中国中西医结合杂志,2023,43(1):45-52. 被引量:1
二级引证文献4
-
1任超,童亚林,姚咏明.高迁移率族蛋白B1介导脓毒症免疫功能障碍研究进展[J].中华急诊医学杂志,2015,24(2):223-226. 被引量:3
-
2任超,童亚林,姚咏明.严重脓毒症胆碱能抗炎通路障碍机制的研究进展[J].中华创伤杂志,2015,31(3):217-219. 被引量:3
-
3孙传伟,曾红科,卞徽宁,刘素玲,罗红敏,熊兵,郑少逸,刘族安,陈华德,赖文.创伤弧菌脓毒性休克死亡三例[J].中华急诊医学杂志,2020,29(9):1226-1228. 被引量:6
-
4余卫东,左池靖,汪杰,刘艳,梁万徽,张婷,彭灿.基于CiteSpace可视化分析牛黄研究热点与趋势[J].现代中药研究与实践,2024,38(2):83-89.
-
1刘凌云,卢永刚,何沙,孟洁.梗阻性黄疸患者免疫功能的变化[J].中国普通外科杂志,2012,21(8):996-999. 被引量:8
-
2郑述铭,林新峰.醒脑静注射液治疗脓毒性脑病的临床研究[J].广州中医药大学学报,2015,32(5):803-807. 被引量:5
-
3张旭,余桂芳,朱科明.脓毒性脑病[J].国际麻醉学与复苏杂志,2012,33(7):480-483. 被引量:2
-
4雷李美,蓝翔,考验,郑浩.参附注射液对严重创伤患者T细胞亚群、天然杀伤细胞及预后的影响[J].中华全科医学,2016,14(5):743-745. 被引量:6
-
5候文英,徐卫华,郁帮俊.溃疡性结肠炎的诊断与治疗现状[J].中国现代医药科技,2004,4(1):85-86.
-
6夏汉兵,刘喜,刘方,陆必森,周刚.脓毒性脑病患儿血清S—100B及神经元特异性烯醇化酶检测的意义[J].医学信息(下旬刊),2010,23(7):3-3. 被引量:1
-
7李雪,孙启.移植肾缺血-再灌注损伤与炎症和微血管病变[J].肾脏病与透析肾移植杂志,2012,21(3):287-290. 被引量:3
-
8戴新贵,艾宇航,邓文琳.脓毒性脑病的预警因素分析(英文)[J].现代生物医学进展,2008,8(10):1884-1889. 被引量:1
-
9王毓锋,施宝民.高脂血症性急性胰腺炎微循环障碍机制研究进展[J].外科研究与新技术,2015,4(1):48-51. 被引量:13
-
10张庆红,姚咏明.加强对脓毒性脑病的研究[J].中华急诊医学杂志,2015,24(2):117-120. 被引量:11