摘要
目的:观察睡眠呼吸暂停综合征(Sleep apnea syndrome,SAS)患者睡眠前后黄斑厚度的改变。方法:选择2003年8月至2007年1月经确诊的在该院门诊和住院部治疗的SAS患者共32例(63只眼),分别在上午11:00～12:00(睡眠前)及患者晨起20～30分钟内(睡眠后)采用相干光断层扫描仪(Optical coherence tomography,OCT)进行黄斑中心凹厚度的测量。结果:睡眠前黄斑中心小凹平均视网膜厚度为(123.00±19.98)μm,睡眠后黄斑中心小凹平均视网膜厚度为(134.25±19.92)μm。睡眠后黄斑中心凹厚度比睡眠前厚度增加(11.25±9.04)μm,95%可信区间为(8.98,13.53)μm,差异有统计学意义(t=9.878,P<0.05)。结论:SAS患者睡眠时的缺血缺氧可以导致黄斑视网膜的水肿增厚。
Purpose：To observe the changes of macular thickness in patients with sleep apnea syndrome（SAS） before and after sleep. Methods：Thirty-two patients（63 eyes） diagnosed as SAS from August 2003 to January 2007 were enrolled.Macular thickness were measured using optical coherence tomography（OCT） at 11：00 - 12：00 evening（before sleep） and 20 - 30 minute after sleep,respectively. Results：The mean macular thickness was（123.00±19.98）μm and（134.25±19.92） μm before and after sleep,respectively.The mean difference was（11.25±9.04）μm before and after sleep（t = 9.878,P 0.05）,95%CI（8.98,13.53）μm. Conclusion：The macular thickness of SAS is increased in SAS patients,which may due to anoxia of SAS.
