摘要
目的:检测部分抗癫痫中成药中是否含有西药抗癫痫药物的成分。方法:用高效液相色谱法测定53种抗癫痫中成药中是否含有苯巴比妥、苯妥英钠、卡马西平和丙戊酸钠。结果:83.01%中成药中测出含有苯巴比妥、苯妥英钠、卡马西平和丙戊酸。结论:市场上大量未标明含有抗癫痫西药成分的中成药,严重影响癫痫用药安全。
Aim:To determine the components of the antiepileptic drugs(AEDs) in some Chinese traditional medicine.Methods:The elements of phenbarbital(PB),phenytoin(PHT),carbamazepine(CBZ) and valproate sodium(VPA) in 53 species for Chinese traditional medicine were measured by HPLC.Results:The AEDs were found in 83.01%of the Chinese traditional medicine.Conclusion:The unmarked components of AEDs in the Chinese traditional medicine have seriously influenced therapeutic efficacy and safety.
出处
《中国临床神经科学》
2011年第2期146-149,共4页
Chinese Journal of Clinical Neurosciences
关键词
抗癫癎药
中药
癫癎
antiepileptic drugs
Chinese traditional medicine
epilepsy