云南玉溪市14851例20～80岁超声及单光子骨密度调查分析

Analysis of bone mineral density measured with QUS and SPA in 14851 residents aged 20-80 years old in Yuxi

目的探讨玉溪市正常人群定量超声(QUS)峰值骨密度(PBD)及正常参考区间并与本院传统的单光子(SPA)骨密度(BMD)检测结果进行对比,了解二者相关性和结果传承。方法回顾性分析玉溪市人民医院健康体检中心2008年1月～2010年6月14851例Sahara超声及单光子骨密度仪检测的骨密度结果,并从体检系统中筛出影响骨密度因素的异常患者,PEMS按年龄分层进行统计分析。结果玉溪市正常人QUS男女PBD分别出现于25岁(0.6895±0.1411 g/cm2)及24岁(0.6884±0.1084 g/cm2),与厂家提供的25～30岁(0.581±0.112 g/cm2)具有统计学差异显著性;SPA男女PBD分别出现于32岁(0.6933±0.0815 g/cm2)及30岁(0.6160±0.0728 g/cm2)。结论 QUS与SPA法测定BMD,由于方法及测量部位的不同,PBD男女有别且出现的年龄段不同;同年龄组QUS与SPA法BMD无可比性(P<0.01),但具有良好的线性关系,只要正确制定本地域参考区间,也能正确反映个体BMD情况。

Objective To explore the peak bone mineral density （PBD） measured with quantitative ultrasound （QUS） and the normal reference range in normal people in Yuxi, and to compare that with the BMD measured with SPA in our hospital to know the correlation of the resuhs. Methods BMD results with either Sahara QUS or SPA measurement were retrospectively analyzed in 14851 cases in the Health Center of People＇ s Hospital of Yuxi city from January 2008 to June 2010. The patients whose BMD could be affected by abnormal factors were not included. PEMS was analyzed according to the age stratification. Results In Yuxi city, PBD in normal males measured with QUS appeared at 25 years old （0. 6895 ± 0. 1411 g/cm2） and in females appeared at 24 years old （0. 6884 ±0. 1084 g/cm2 ） , respectively. Statistic difference existed comparing to PBD at 25-30 years old （0. 581 ±0. 112 g/cm2） provided by the company. PBD in normal males measured with SPA appeared at 30 years old （0. 6933 ±0. 0815 g/cm2 ） and in females appeared at 32 years old （0. 6160 ±0. 0728 g/cm2）. Conclusion The PBD measured with QUS or SPA is different due to the difference of the method and the measurement sites. PBD is different in different gender and age groups. There is no comparability between two measure methods at the same age group, but there is nice linear correlation. It can reflect personal BMD by making right reference range.