摘要
AIM:In order to identify the HPTLC profile(bio-marker),at species level,for the identification and confirmation of crude drugs,HPTLC separation was initiated on different parts of Aerva lanata L.from South India.METHODS:Preliminary phyto-chemical screening was done by the method of Harborne.HPTLC studies were carried out following Harborne and Wagner et al method.The Ethyl acetate-ethanol-water(8:2:1.2)was employed as mobile phase for glycosides.RESULTS:The methanolic extract of stem,leaves,root,flowers and seeds of A.lanata showed the presence of 23 different types of glycosides with 23 different Rf values with range 0.02 to 0.86.In general higher degree of glycoside diversity has been observed in vegetative parts when compared to the reproductive part.Maximum number(12)of glycosides has been observed in root followed by stem(9).CONCLUSION:The results of the present study supplemented the folkloric usage of the studied plants which possess several known and unknown bioactive com-pounds with bio-activity.By isolating and identifying these bioactive compounds new drugs can be formulated to treat various diseases.
AIM:In order to identify the HPTLC profile(bio-marker),at species level,for the identification and confirmation of crude drugs,HPTLC separation was initiated on different parts of Aerva lanata L.from South India.METHODS:Preliminary phyto-chemical screening was done by the method of Harborne.HPTLC studies were carried out following Harborne and Wagner et al method.The Ethyl acetate-ethanol-water(8:2:1.2)was employed as mobile phase for glycosides.RESULTS:The methanolic extract of stem,leaves,root,flowers and seeds of A.lanata showed the presence of 23 different types of glycosides with 23 different Rf values with range 0.02 to 0.86.In general higher degree of glycoside diversity has been observed in vegetative parts when compared to the reproductive part.Maximum number(12)of glycosides has been observed in root followed by stem(9).CONCLUSION:The results of the present study supplemented the folkloric usage of the studied plants which possess several known and unknown bioactive com-pounds with bio-activity.By isolating and identifying these bioactive compounds new drugs can be formulated to treat various diseases.
出处
《中国天然药物》
SCIE
CAS
CSCD
北大核心
2011年第3期210-214,共5页