1Tanssig LM,Wright AL Holberg CJ,et al.Tucson children's respiratory study:1980 to present[J].J Allergy Clin Immunol,2003,111(4):661-675.
2Kurukulaaratchy RJ,Fenn MH,Waterhouse LM,et al.Characterization of wheezing phenotypes in the first 10 years of life[J].Clin Exp Allergy,2003,33(5):573-578.
3Fajt ML,Wenzel SE.Asthma phenotypes in adults and clinical implications[J].Expert Rev Respir Med,2009,3 (6):607-625.
4Moore WC,Meyers DA,Wenzel SE,et al.Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program[J].Am J Respir Crit Care Med,2009,181(4):315-323.
5ten Brinke A,Zwinderman AH,Sterk PJ,et al."Refractory" eosinophilic airway inflammation in severe asthma:effect of parenteral corticosteroids[J].Am J Respir Crit Care Med,2004,170(6):601-605.
7Wenzel SE,Schwartz LB,Langmack EL,et al.Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics[J].Am J Respir Crit Care Med,1999,160(3):1001-1008.
8Wenzei SE.Asthma:defining of the persistent adult phenotypes[J].Lancet,2006,368(9537):804-813.
9Chung KF,Godard P,Adelroth E,et al.Difficult/therapyresistant asthma:the need for an integrated approach to define clinical phenotypes,evaluate risk factors,understand pathophysiology and find novel therapies.ERS Task Force on Difficult/Therapy-Resistant Asthma.European Respiratory Society[J].Eur Respir J,1999,13(5):1198-1208.
10ANON.Proceedings of the ATS workshop on refractory asthma:current understanding,recommendations,and unanswered questions.American Thoracic Society[J].Am J Respir Crit Care Med,2000,162(6):2341-2351.