摘要
目的:探讨白介素-2联合博莱霉素治疗恶性胸腔积液的疗效。方法:郑州大学第一临床医学院呼吸内科确诊的恶性胸腔积液患者205例,博莱霉素组90例,给予博莱霉素60 mg治疗;白介素-2联合博莱霉素组115例,给予白介素-2 200万U联合博莱霉素60 mg冶疗。结果:博莱霉素组与白介素-2联合博莱霉素组总有效率分别为75.6%和88.7%,差异有统计学意义(P<0.05)。结论:胸腔内交替注入白介素-2与博莱霉素治疗恶性胸腔积液较单用博莱霉素疗效好,可以作为治疗恶性胸腔积液的有效方法。
Objective：To evaluate the efficacy and safety of Interleukin-2 combined with bleomycin. Methods：205 with malignant pleural effusion in our department were analyzed retrospectively.90 cases in bleomycin group（A group） were treated by bleomycin 60 mg.115 cases in Interleukin-2 combined with bleomycin group（B group） were treated by 60 mg of bleomycin and 2 000 000 units of Interleukin-2. Results：The total efficiency of A group and B group was 75.6% and 88.7%.There was significant difference（P0.05）. Conclusion：Intrapleural injection with interleukin-2 combined with bleomycin is effective for patients with malignant pleural effusion than those with bleomycin group.It deserves further applications.
出处
《河南医学研究》
CAS
2011年第1期67-69,共3页
Henan Medical Research
