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HIF-1α、VEGF、iNOS在消化性溃疡中的表达及中药的干预效应 被引量:9

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摘要 低氧诱导因子-lα(HIF-1α)是一个在介导多细胞和系统对缺氧及缺血稳态反应中发挥关键作用的核转录因子,了解其特殊的生物学特性以便可以调控相关目的基因,如血管内皮细胞生长因子(VEGF)、诱导型一氧化氮合酶(iNOS)的表达,对认识因组织缺血缺氧有关的消化性溃疡的病理生理过程有重要意义。HIF-1α作为基因调节靶点将成为消化性溃疡预防和治疗的新途径。
作者 李芳 葛惠男
出处 《吉林中医药》 2011年第4期320-322,共3页 Jilin Journal of Chinese Medicine
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参考文献17

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