不同方案治疗非肥胖型多囊卵综合征的临床疗效评价

The different plan treats the clinical curative effect appraisal which the non-obese multi-pouch egg synthesis drafts

多囊卵巢综合征（ PCOS） 是由神经、内分泌及代谢系统调控因素失衡引起的疾病,是涉及内分泌、代谢等诸多因素的终身性疾病.其发病率占育龄妇女的5-10%,占无排卵性不孕中的75%.自1935年stein和leven首次报道该病以来,一直是妇产科领域研究的热点,PCOS在世界不同国家的表现多种多样,而在同一个国家的不同民族之间也存在着差异.有研究对美国、日本和意大利的PCOS患者进行了比较,指出日本的PCOS妇女肥胖的发生率比较低,中国PCOS患者的多毛的严重程度要比欧美国家轻,肥胖的发生率与日本的PCOS的患者相近,远比欧美国家低,且由于诊断水平的提高,很多PCOS患者在出现肥胖前就能诊断和治疗,进一步增加了非肥胖型PCOS的比例.避孕药联合二甲双胍治疗肥胖型PCOS的疗效已经得到肯定,但对于非肥胖型PCOS是否同样有效报道极少.本研究旨在探讨加用二甲双胍治疗非肥胖型PCOS是否同样有效,进一步指导临床用药.

The multi-pouch ovary synthesis drafts （PCOS） is disease which by the nerve,endocrine and metabolism system reg- ulation factor causes unbalancedly,is involves the internal secretion,metabolism and so on many factor lifelong diseases. Its disease incidence rate occupies the woman of child-bearing age 5-10% ,occupies without ovulation sterile 75%. Since 1935 stein and leven reported for the first time should get sick, always is the gynecology and obstetrics department domain research hot spot, PCOS in the world different country performance many and varied, but also has the difference in between the identical national different nationality. Had the research to American, Japanese and Italy＇s PCOS patient has carried on the comparison, pointed out Japan＇s PCOS woman＇s obese formation rate quite was low,the Chinese PCOS patient＇s pilosity serious degree had to be lighter than the European and American countries,the obese formation rate and Japan＇s PCOS patient was close,was far lower than the European and American countries also as a result of the diagnosis level enhancement, the very many PCOS patient in appears obese front can diagnose and treat, further increased the non-obese PCOS proportion. The contraceptive united two armor biguanide treatment obese PCOS the curative effect already to obtain the affirmation, but extremely were whether few regarding the non-obese PCOS similarly effective report. This research is for the purpose of discussing adds treats nonobese PCOS with two armor biguanides similarly is whether effective,further instructs the clinical medication.