腹腔镜手术后联合孕三烯酮治疗子宫内膜异位症的临床观察

Peritoneoscope surgery to be pregnant three ketenes to treat the endometriosis jointly clinical observation

目的：研究子宫内膜异位症患者在腹腔镜手术后联合孕三烯酮治疗的疗效及安全性、可行性.方法：将100例子宫内膜异位症行腹腔镜手术后的患者随机分为两组：单纯手术组45例为观察组,手术后服用孕三烯酮组55例为对照组,于月经周期第一天开始服用孕三烯酮2.5mg,每周2次,连续6个月.所有患者随访1-3年.结果观察组有效率34.7%,改善率17%,复发率31.1%,术后妊娠率2.2%,而对照组有效率80%,改善率21.8%,复发率12.7%,术后妊娠率12.7%,两组比较差异有显著性（P〉0.05）,服药组在服药期间未出现严重副作用,仅有5例转氨酶轻度增加,经护肝治疗后恢复正常.结论：腹腔镜术后联合孕三烯酮治疗子宫内膜异位症效果好,复发率低,是一种安全有效的治疗方法.

Objecitve：The research endometriosis patient is pregnant jointly after the peritoneoscope surgery three ketene treatment curative effect and the security, the feasibility. Methods： Divides into two groups stochastically after 100 example endometriosis good peritoneo- scope surgery patient：The pure surgery group 45 examples are the observation group, after the surgery take are pregnant three ketene group 55 examples are the control groups, first day starts in the menstrual cycle to take is pregnant three ketene 2. 5rag, each week 2 times, continual 6 months. All patients make a follow-up visit for 1 -3 year. Finally observation group effectiveness 34. 7% ,improvement rate 17% ,recurrence rate 31.1%, after technique rate of pregnancy 2.2 %, but control group effectiveness 80 %, the improvement rate 21.80%, the recurrence rate 12. 7% ,after the technique the rate of pregnancy 12.7% ,two grop of comparison differences have the significance （P〉0. 05）, takes medicine the group in takes medicine the period not to appear the serious side effect,only some 5 example transaminase mild increase, after protects the liver treatment to restore norrlmlly. Conclusion： After the peritoneoscope technique is pregnant three ketenes to treat the endometriosis effect jointly to be good, the recurrence rate is low,is one security effective method of treatment.