280例患病新生儿全血中14种元素变化的研究

The Determination of 14 Elements in Whole Blood in 280 Newborn Babies with Diseases

于１９９７年６月～１９９８年１０月间对２８０例患４种常见病新生儿全血中１４种元素进行了检测，并与正常足月、顺产新生儿１００例对比。结果表明：（１）Ｇ－６ＰＤ缺陷引起的高胆红素血症组与正常组对照，男、女Ｆｅ，Ｚｎ均低于正常组；男、女Ｃｕ，均高于正常组。（２）缺氧缺血性脑病组与正常组对照，男、女Ｚｎ、Ｆｅ、Ｃａ均低于正常组；男、女Ｃｕ、Ｍｇ、Ｃｏ均高于正常组。（３）硬肿症组与正常组对照，男、女Ｚｎ、Ｆｅ均低于正常组；男、女Ｍｇ、Ｃｕ均高于正常组。（４）足月小样儿组与正常组对照，男、女Ｆｅ、Ｚｎ、Ｃｏ均低于正常组，余无异常。

To study the relations between the diseases and trace elements in newborn badies,from June 1997 to October 1998,the changes of 14 kinds of trace elements in whole blood of newborn babies with 4 kinds of common diseases (hyperbilirubinemia of newborn resulted from deficiency of G-6PD,anoxic and ischemia encephalopathy,scleroberma of newborn,and small for date infant)were discussed.The results showed that,the levels of Fe and Zn were less than normal( P <0 01) while the level of Cu as heigher than normal( P <0 05).The anoxic and ischemia encephalopa thy and those of normal Group were compared and the levels of Zn,Ca and Fe were less than normal ( P <0 01 respectively),the levels of Cu,Mg and Co were heigher than normal ( P <0 01, P <0 05, P <0 01 respectively).As per comparision between scleroderma and that of normal group,the levels of Zn and Fe were less than normal ( P <0 01);the levels of Mg and Cu were heigher than normal ( P <0 05, P <0 01 respectively).By the comparision between small for date infant and that in the normal group,the levels of Fe and Zn,Co were less than normal.