33例新生儿先天性膈疝

Clinical analysis of congenital diaphragmatic hernia in newborn infants： report of 33 cases

目的 分析新生儿先天性膈疝的临床表现及诊治经验,以提高先天性膈疝病婴手术成功率及生存质量.方法 回顾性分析2004年1月至2009年9月新生儿重症监护室收治的33例先天性膈疝新生儿临床表现及治疗结果.结果 33例先天性膈疝中21例行手术治疗,术后生存17例,其中4例产前经超声检出者术后均生存.死亡4例,死因与肺发育不良有关.12例未行手术者全部死亡,其中1例生后即刻死亡.结论 新生儿先天性膈疝的病死率较高,应加强产前诊断及产科、新生儿科、小儿心胸外科的合作以提高先天性膈疝病婴的生存率.

Objective To review the clinical experience of diagnosis and treatment of the congenital diaphragmatic hernia in newborn infants. Methods Thirty-three neonates were diagnosed having congenital diaphragmatic hernia in our hospital from Jan. 1,2004 to Sept. 30, 2009. The clinical data was retrospectively reviewed. Results 21 cases were treated surgically and 17 survived, while 4 cases died. The main cause of death was congenital pulmonary dysplasia. Another 12 cases refused to accept surgical treatment and they all died, one died shortly after he was born. Four cases who had been diagnosed by prenatal ultrasonography were survived. Conclusion The mortality of congenital diaphragmatic hernia in neonates was still high. Prenatal diagnosis of the congenital diaphragmatic hernia is very important and the cooperation between the obstetrics, neonatology and cardiothoracic surgery will improve the survival rate of congenital diaphragmatic hernia in newborn infants.