2Bimbaum H,Pike C,Kaufman R,et al.Societal cost of rheumatoid arthritis patients in the US.Curt Med Res Opin,2010,26:77-90.
3Yelin E,Wanke LA.An assessment of the annual and long-term direct costs of rheumatoid arthritis:the impact of poor function and functional decline.Arthritis Rheum,1999,42:1209-1218.
4Pugner KM,Scott DI,Holmes JW,et al.The costs of rheumatoid arthritis:an international long-term view.Semin Arthritis Rheum,2000,29:305 -320.
5Birnbaum HG,Barton M,Greenberg PE,et al.Direct and indirect costs of rheumatoid arthritis to an employer.J Occup Environ Med,2000,42:588-596.
6Weinblatt ME,Keystone EC,Furst DE,et al.Adalimumab,a fully human anti-tumor necrosis factor alpha monoclonal antibody,for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate:the ARMADA trial.Arthritis Rheum,2003,48:35-45.
7Weinblatt ME,Keystone EC,Furst DE,et al.Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis:ARMADA 4 year extended study.Ann Rheum Dis,2006,65:753-759.
8Keystone EC,Kavanaugh AF,Sharp JT,et al.Radiographic,clinical,and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy:a randomized,placebo-controlled,52-week trial.Arthritis Rheum,2004,50:1400-1411.
9Keystone EC,Kavanaugh A,van der Heijde D,et al.Long-term impact of adalimumab plus methotrexate on radiographic,clinical,and functional progression of rheumatoid arthritis.73rd Annual Scientific Meeting of the American College of Rheumatology (ACR) and the 44th Annual Meeting of the Association of Rheumatology Health Professionals (ARHP).Philadelphia,2009.
10Breedveld FC,Weisman MH,Kavanaugh AF,et al.The PREMIER study:A multicenter,randomized,double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early,aggressive rheumatoid arthritis who had not had previous methotrexate treatment.Arthritis Rheum,2006,54:26-37.