蜂蜜用于皮肤软组织擦挫创面感染的临床研究

Effect of honey dressing used for skin and soft tissue abrasion with wound infection

目的探讨自制蜂蜜敷料治疗皮肤软组织擦挫创面感染的临床效果。方法复习相关文献,分析蜂蜜的理化特性及药效机制;将入选的125例患者按随机数字表法分为试验组和对照组;试验组65例,采用自制的蜂蜜敷料换药,每日1次,感染控制后,2~3 d换药1次,直至愈合;对照组60例,采用传统方法凡士林油纱换药;观察两组疼痛程度、创面感染控制及愈合时间。结果试验组与对照组疼痛计分分别为（1.97±0.61）、（5.63±0.92）分,差异有统计学意义（P〈0.01）,试验组换药疼痛轻;试验组创面感染控制及愈合时间明显少于对照组,差异有统计学意义（P〈0.01）。结论蜂蜜敷料能及时有效的控制感染,促进创面修复。

OBJECTIVE To evaluate the efficacy of honey dressing using for skin and soft tissue abrasion with wound infection.METHODS A total of 125 patients were randomly divided into two groups.65 patients in experimental group were covered with honey dressing,once a day.After wound infection controlled,the dressings was changed to once every three days until the wound healed.60 patients in control group received vaseline dressings only.The infection control time,healing time and pain sensation were compared.RESULTS There was a decreased pain sensation in the experimental group,the scores of pains in experimental group and control group were（1.97±0.61） and（5.63±0.92）,respectively.The experimental group had significantly shorter wound infection control time and healing time than the control group,with significant differences（P0.01）.CONCLUSION Honey dressing is one of the best method for treating skin and soft tissue abrasion with wound infection and can promote the wound healing.