控制抗菌药物皮内过敏试验假阳性的方法研究

Methods to control false-positive in intradermal allergy test of antibiotics

目的分析抗菌药物皮内过敏试验假阳性率高的原因,探索解决方法。方法细化抗菌药物皮内过敏试验操作流程和结果判断方法,对护士进行集中理论培训、操作示教和跟班带教,严格控制判断抗菌药物阳性的标准和权限,总结分析应用此方法1年青霉素类和头孢类抗菌药物皮内过敏试验结果。结果 2008年2月-2009年2月头孢类抗菌药物皮内过敏试验阳性率为0.37%、青霉素类为0.11%,所有抗菌药物皮内过敏试验阴性患者均按规定用药,未发生急性药物过敏现象。结论应用该方法能有效控制抗菌药物皮内过敏试验假阳性率。

OBJECTIVE To analyze the reasons of higher antibiotic false positive rate of intradermal allergy testing,and find methods to reduce antibiotic false positive rate of intradermal allergy testing.METHODS We refined the process and results determine of antibiotics intradermal allergy test,with strict theoretical training and operation teaching.We summarized and analyzed the data of penicillins and cephalosporins intradermal allergy test for 1 year.RESULTS Intradermal allergy tests positive rate of penicillin and cephalosporins were 0.11%and 0.37% from 2008 to 2009.No acute drug allergy phenomenon occurred in patients with the negative intradermal allergy test.CONCLUSION This method can effectively reduce the false positive rate of antibiotics intradermal allergy tests.