2005-2009年凉山临床常见病原体及其耐药性

Common clinical pathogens and theirs resistance during 2005-2009

目的掌握凉山临床常见病原体及其耐药性。方法按照《全国临床检验操作规程》进行细菌培养;普通细菌鉴定及药敏试验用MicroScan阳性、阴性复合检测板,苛养菌药敏试验用K-B纸片法;统计2005年7月-2009年6月相关资料。结果临床分离病原体3944株,革兰阳性菌1037株,占26.3%,革兰阴性菌2374株,占60.2%,真菌367株,占9.3%,泌尿道支原体166株,占4.2%;分离菌前3位为葡萄球菌属、大肠埃希菌、假单胞菌属分别占16.6%、13.4%、9.7%;标本前3位为下呼吸道分泌物、血及骨髓、脓液等分泌物分别占47.4%、18.3%、13.2%;鲍氏不动杆菌对亚胺培南的敏感率下降至28.6%;耐甲氧西林凝固酶阴性葡萄球菌检出率达87.8%。结论病原体耐药形势严峻,必须认真预防控制。

OBJECTIVE To grasp the common clinical pathogens and drug resistance in the Liangshan.METHODS Bacteria Culture in accordance with National Guide to Clinical Laboratory Procedures.Common bacterial identification and drug sensitive testing use MicroScan G＋ or G-panel,Susceptibility test of fastidious bacteria using K-B method.The related data from Jul 2005 to Jun 2009 was analyzed.RESULTS Clinical isolated pathogens were 3944 strains,G＋ bacteria（except candida） 26.3%,G-bacteria 60.2%,Candida 9.3%,mycoplasma 4.2%.The leading three bacteria were Staphylococcus,Escherichia coli and Pseudomonas,accounting for 1636%,13.4% and 9.7%.The leading 3 specimen were lower respiratory tract secretions,blood and bone marrow and pus and other secretions of infected sites accounting for 47.4%,18.3% and 13.2%,A.baumannii sensitive rate to imipenem declined to 28.6%;The detection rate of methicillin-resistant Staphylococcus aureus reached 87.8%.CONCLUSION Bacterial resistance situation is serious,which must be carefully controlled and prevented.