不同大小肾通道对猪肾动脉损伤的实验研究

An experimental study measuring arterial injury in vitro porcine kidney in different sizes of nephrostomy tracts

目的探讨不同大小肾通道对离体猪肾动脉的损伤情况。方法应用经皮肾技术在离体猪肾上分别建立12、14、16……32 F11组通道，每组40个通道。利用数字减影血管造影技术对离体猪肾动脉造影并分析各组通道对肾动脉的损伤情况。结果在12-32F范围内，肾动脉的损伤程度随肾通道直径的增加而递增。20F和32F通道相比，有肾动脉损伤的通道数分别为18个和30个，差异有统计学意义（P〈0．05）。18、20、22F各组通道对肾动脉损伤之间差异无统计学意义（P〉0．05）。结论随肾通道直径的增大，肾动脉损伤的程度逐渐增加。20F较32F肾通道能够明显减少肾动脉的损伤。

Objective To investigate the arterial injury in vitro porcine kidney to different size of nephrostomy tracts. Methods The technique of percutaneous nephrostomy was applied to establish 11 groups of different size of nephrostomy tracts from 12 F to 32 F, with 40 tracts in every group. The technique of digital subtraction angiography （DSA） was used to inspect and analyze arterial injury. Results In the range from 12 F to 32 F, the damage of arterial injury increased with the size of the tract diameter. In groups of 20 F and 32 F, the number of nephrostomy tracts with serious arterial injury was 18 （18/40） and 30 （30/40） respectively, and the difference was statistically significant （P^0.05）. There was no statistical difference between groups 18 F.20 F.and 22 F. Conclusions The damage of renal arterial injury increased with the size of the nephrostomy tract. Atract of 20 F reduces arterial injury compared with a tract of 32 F.