肌钙蛋白两个亚单位在急性心肌梗死诊断中的应用分析

Application of subunits of troponinin diagnosis of acute myocardial infarction

目的:探讨肌钙蛋白I(cTnI)和肌钙蛋白T(cTnT)在急性心肌梗死(AMI)诊断中的意义。方法:对89例AMI患者和25例非AMI患者以及48例AMI患者胸痛发作后不同时间cTnI、cTnT、肌红蛋白(MYO)检测值及阳性率进行比较,并比较不同浓度组cTnI、cTnT检测值和阳性率。结果:AMI组患者cTnI、cTnT、MYO检测值及阳性率均明显高于非AMI组(P<0.05);48例AMI患者随着胸痛发作时间延长,cTnI、cTnT检测值及阳性率有上升的超势(P<0.05),MYO检测值和阳性率有下降的趋势(P<0.05);高浓度组cTnI、cTnT检测值明显高于低浓度组(P<0.05)。结论:cTnT和cTnI在诊断AMI方面是相似的;而作为再灌注溶栓治疗的观察,cTnI更优于cTnT。

Objective：To explore the value of cardial troponin I（cTnI） and cardial troponin T（cTnT） in diagnosis of acute myocardial infarction（AMI）.Methods：Levels and positive rates of cTnI,cTnT and myoglobin（MYO） at different time of 89 cases with AMI,25 cases without AMI and 48 AMI cases with attack of chest pain were determined.And levels and positive rates of cTnI and cTnT were compared among different groups.Results：Levels and positive rates of cTnI,cTnT and MYO were significantly higher in AMI group（P0.05）.cTnI and cTnT increased while MYO decreased as the prolonged attack duration of chest pain（P0.05）.The levels of cTnI and cTnT were significantly higher in high concentration group（P0.05）.Conclusions：cTnI and cTnT are valuable in diagnosis of AMI.And cTnI is more valuable in reperfusion thrombolysis.