儿科住院患儿合并医院感染相关因素对照研究

Correlative factors for combined nosocomial infection in pediatric inpatients:a case-control study

目的探讨住院患儿合并医院感染的相关因素。方法 2007年5月-2010年5月发生医院感染的42例患儿作为观察组,按照1∶2配比设立对照组,对两组患儿可能引起医院感染的相关变量进行单因素分析与logistic回归分析。结果单因素检验2χt、检验显示,9个变量是引起医院感染的相关因素(P<0.05),与性别构成、体重无关;logistic回归分析,筛选出独立相关因素:年龄小、实施侵入性操作、预防应用抗菌药物、重症监护(参数估计值分别为8.89、8.12、5.98、7.56)差异有统计学意义(P<0.05),OR值分别为3.34、2.79、2.47、2.14。结论住院患儿合并医院感染发生率较高,是多因素综合作用的结果,应针对相关因素采取相应的预防措施。

OBJECTIVE To explore the correlative factors of influencing the combined nosocomial infection in pediatric patients.METHODS A total of 42 cases with nosocomial infection were set as the observation group,while the control group was established in accordance with the ratio of 1∶2.The single factor analysis and logistic regression analysis were performed to the correlative variables that may influencing the nosocomial infection.RESULTS Single factor（χ2 test,t-test） showed that 9 variables were the influencing factors of nosocomial infection（P〈0.05）,and unrelated to gender,weight（P〉0.05）,The independent factors,including age,implementation of invasive operation,prevention of antibiotics and intensive care,were screened out by Logisticregression analysis,respectively（P〈0.05）,with ORvalue of 2.79,3.34,2.14 2.47 and 2.14,respectively.CONCLUSION The incidence of combined nosocomial infection in pediatric inpatients is high,which is a comprehensive effect of multiple factors.The corresponding preventive measures should be taken in accordance with the correlative factors.