重组人干扰素a-2b栓治疗人乳头状瘤病毒感染宫颈糜烂的临床疗效观察

Recombinant human interferon a-2b suppository on treatment of cervical erosion caused by human papillomavirus infection:a clinical observation

目的观察重组人干扰素a-2b栓对人乳头状瘤病毒（HPV）感染引起的宫颈糜烂的疗效。方法 128例宫颈糜烂,实验室检查证明有HPV感染的患者,随机分为两组,试验组使用重组人干扰素a-2b栓,对照组使用甲硝唑泡腾片。结果治疗1~2个疗程后,重组人干扰素a-2b栓的有效率为81.25%,甲硝唑泡腾片组有效率为51.5%,两组疗效比较差异有统计学意义（P〈0.05）。结论重组人干扰素a-2b栓治疗HPV感染引起的宫颈糜烂疗效显著。

OBJECTIVE To observe the effect of recombinant human interferon a-2b suppository in treating cervical erosion caused by HPV infection.METHODS A total of 128 cases of cervical erosion,confimed by TCT examination were randomly divided into two groups to observe the group using recombinant human interferon a-2b bolt,Control group with metronidazole effervescent tablets.RESULTS After 1-2 courses of treatment,recombinant human interferon a-2b with the effective rate of 81.25% was more effective than metronidazole suppositories effervescent tablets group with the effective rate of 51.5%,the difference of effect between the two groups was statistically significant（P〈0.05）.CONCLUSION Recombinant human interferon a-2b suppository in the treatment of cervical erosion caused by HPV infection has a significant effect.