PAMAM树形高分子等含氮有机物的荧光研究进展

Progress in a New Type of Fluorescence Emission from Nitrogen-containing Organic Compounds

近年来不具有典型荧光基团的PAMAM树形高分子等含氮有机物被发现可发射强烈荧光,引起了广泛的关注。实验结果表明多种因素,如分子结构、分子量、氧化、酸化、介质和陈化过程等,均对荧光的强度和荧光峰位置产生影响。与传统有机荧光物质相比,这类含氮有机物荧光物不仅具有生物相容性好和水溶性高的特性,还具有易于功能化改性和制备相对简单的优点,所以在绿色发光材料和生物医药领域有着广阔的应用前景。本文综合评述了这类荧光现象的发现背景、研究状况和荧光性能及其应用实例;初步分析了荧光机理,并指出这类荧光研究中尚未解决的问题和发展方向。

The interesting blue emission from poly （amido amine） （PAMAM） dendrimers and dendritic polymers as well as small molecules containing amino group, in which case there is no traditional fluorophore unit in the structure,was reproted in recent years. The intensity of fluorescence was found to vary by changing experimental conditions such as pH value, aging time, temperature,and adding oxidant. Compared to organic materials bearing traditional fluorescent chromophore, this new kind of organic fluorophores can find applications in many fields, especially in the biomedical field, because this kind of materials possesses excellent biocompatibility and unique mimic properties of biological macromolecules. To summarize the important results of recent studies,this review shows the optimal conditions, application challenge, fluorescence merit and its attractive property. The trends of research and development of this new kind fluorescence are also described.