老年与中青年肺部感染肺阴伤证的比较研究

Comparison of lung-yin injury syndrome between the aged and the middle-aged and young people with pulmonary infection

目的比较老年与中青年肺部感染肺阴伤证发生的特点及相关影响因素,为临床辨治提供依据。方法共观察肺部感染患者162例,其中老年组102例,中青年组60例。比较2组肺阴伤证的发生率;观察基础疾病与肺阴伤证的关系,肺阴伤证与病程的关系,体质因素与肺阴伤证的关系。比较老年组与中青年组肺部感染呼吸系统症状;观察老年肺部感染肺阴伤证的临床特点。结果肺部感染患者肺阴伤证总发生率为39.5%,老年组发生率为53.9%,中青年组发生率为15.0%,老年组发生率明显高于中青年组（P〈0.05）。有慢性呼吸系统疾病、糖尿病、脑梗死等基础病的患者发生肺阴伤的机率更高。老年组肺部感染肺阴伤证发生率7 d内为23.6%,8~14 d为34.5%,15 d以上为41.8%;中青年组肺部感染肺阴伤证发生率7 d内为2.0%,8~14 d为40.2%,15 d以上为58.1%。64例发生肺阴伤证的患者中阴虚质者30例,占46.9%。老年组喘息症状发生率高于中青年组（P〈0.05）。结论老年肺部感染肺阴伤证发生率高于中青年,肺阴伤证表现可见于发病全程;基础疾病、体质因素及用药等可影响患者肺阴伤证的发生率。

Objective To compare the characteristics and relevant influence factors of lung-yin injury syndrome between the aged and the middle-aged and young people with pulmonary infection,and provide the basis for clinical differentiation and treatment.Methods There were totally 162 patients with pulmonary infection being observed and 102 in the aged group and 60 in the middle-aged and young group.The incidence rate of lung-yin injury syndrome was compared between two groups.The relationships between lung-yin injury syndrome and basic diseases,disease course and constitutional factors were observed.The symptoms of respiratory system were compared between the aged group and middle-aged and young group,and the clinical characteristics of lung-yin injury syndrome of senile pulmonary infection were observed.Results The total incidence rate of lung-yin injury syndrome was 39.5% in the pulmonary infection patients.The incidence rate was 53.9% in the aged group and 15.0% in the middle-aged and young group,which was much higher in the aged group than that in the middle-aged and young group（P0.05）.The patients with chronic basic diseases of respiratory system,diabetes and cerebral infarction had a higher incidence rate.The incidence rate in the aged group was 23.6% within 7 days,34.5% from 8 days to 14 days,and 41.8% over 15 days,and in the middle-aged and young group,5% within 7 days,40% from 8 days to 14 days,and 58% over 15 days.Among 64 patients with lung-yin injury syndrome,there were 30 cases with yin-deficiency constitution（46.9%）.The incidence rate of dyspnea was higher in the aged group than that in the middle-aged and young group（P0.05）.Conclusion The incidence rate of lung-yin injury syndrome is higher in the aged patients with pulmonary infection than that in the middle-aged and young patients.The manifestations of lung-yin injury syndrome can be observed in the whole course of pulmonary infection.The incidence rate can be influenced by some factors,like basic diseases,constitution types and medicinal.