治疗女性精神分裂症时利培酮与氯丙嗪对心电图的影响

Influence on ECG of risperdal and chlorpromazine treatment on female schizophrenia patients

目的探讨利培酮与氯丙嗪对心电图的影响。方法使用日本NEC-3370型自动分析机,收集新乡医学院第二附属医院2010年6月-12月间入住的女性精神分裂症病人数,分别服用利培酮(130例)或氯丙嗪(120例),疗程8周,对心电图异常率的对比。结果利培酮组130例中心电图异常19例,其异常率为14.9%,氯丙嗪120例,心电图异常84例,其异常率68.5%,差异有显著意义(P(0.05)。结论女性精神分裂症服用利培酮对心脏的影响明显低于氯丙嗪。

Objective To discuss the influence on ECG of risperdal and chlorpromazine treatment.Methods Using Japanese NEC-automatic analysis machine 3370,collecting the amount of the female schizophrenia patients within the hospital between June-December 2010,treated respectively with risperdal（130 cases） and chlorpromazine（120 cases）,period of treatment for eight weeks,comparing abnormal ECG rates.Results Risperidal was 19 abnormal cases of 130 cases,the abnormal rate for 14.9%,chlorpromazine is 84 abnormal cases of 120 cases,and the abnormal rate 68.5%,there is a significant difference（P0.05）.Conclusions To cardiac affects of risperdal treatment is obviously lower than chlorpromazine of female schizophrenia patient.