早期乳腺癌部分乳腺加速放疗

Accelerated partial breast irradiation for early breast cancer

随着乳腺癌术后复发模式的研究进展，部分乳腺照射方法成为乳腺癌放疗的热点。组织问插植、球囊近距离治疗、术中放疗及三维适形放疗和调强放疗等部分乳腺加速放疗已进入临床研究。其局部控制率和安全性与全乳腺照射比较相当，同时具有治疗周期短、方便患者等优势。部分乳腺加速放疗在部分患者有望代替全乳腺放疗，成为早期乳腺癌保乳术后放疗的标准治疗之一。

With a view to patterns of local recurrence after breast conserving surgery, whole breast irradiation（WBI） after surgery is controversial and partial-breast irradiation（PBI） came up. Many clinical trials related with accelerated partial-breast irradiation using a variety of radiotherapeutic techniques such as interstitial brachytherapy （IBT）, MammoSite Radiation Therapy System, intraoperative radiotherapy （IORT）, threedimensional conformal radiotherapy（3-DCRT）and intensity modulated radiation therapy（IMRT） in selected patients have been carried out. Accelerated partial-breast irradiation that provides faster, more convenient treatment demonstrates local control rate and safety comparable to that of whole breast irradiation. Partial breast irradiation may be an alternative way to whole breast radiotherapy and will be one of the standard treatments in women with early breast cancer seeking breast eonservation.