摘要
目的 :比较国产与进口洛伐他汀治疗高脂血症的疗效。方法 :2 0 6例原发性高脂血症病人分为国产组 113例 (男性 68例 ,女性 45例 ,年龄 5 6a±s10a) ,给国产洛伐他汀 2 0mg ,po ,qd× 8wk ;进口组 93例 (男性 5 8例 ,女性 35例 ,年龄 5 7a±10a) ,给进口洛伐他汀 2 0mg ,po ,qd× 8wk。结果 :国产与进口洛伐他汀治疗前后所降低总胆固醇(TC)、三酰甘油 (TG)和低密度脂蛋白胆固醇 (LDL_Ch)差异均有显著意义 (P <0 .0 5 ) ,但 2组间比较差异无显著意义 (P >0 .0 5 )。结论 :国产与进口洛伐他汀有相似的调节血脂效果 。
AIM: Domestic lovastatin vs imported lovastatin in treating hyperlipidemia. METHODS: Two hundred and six patinets with hyperlipidemia were divided into 2 groups. Domestic group of 113 patients (M 68, F 45, age 56 a±s 10 a) received domestic lovastatin tablet 20 mg, po, qd, for 8 wk. Imported group of 93 patients (M 58, F 35;age 57 a±10 a) received imported lovastatin tablet 20 mg, po, qd, for 8 wk. RESULTS: Differential value of lowing total cholesterol (TC), triglyceride (TG), and low_density lipoprotein cholesterol ( LDL _ Ch ) in two groups all showed significant reductions ( P < 0.05), which had no significant difference between the 2 groups (P>0.05). CONCLUSION: Domestic lovastatin is an effective and safe drug in treating hyperlipidemia as well as imported.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
1999年第5期270-272,共3页
Chinese Journal of New Drugs and Clinical Remedies
关键词
洛伐他汀
血脂过多
胆固醇
高脂血症
治疗
lovastatin
hyperlipidemia
cholesterol
triglycerides
lipoproteins