摘要
目的筛选出最佳的肠健片制粒工艺条件.方法采用单因素考察方法,以其成型性、溶解性、抗吸湿性等为指标,筛选出其处方中加入辅料的种类、配比及最佳的成型工艺条件.结果确定最佳成型工艺条件为干浸膏粉与辅料的比例为1∶2,用85%乙醇溶液制颗粒,其用量为30%-35%.结论该处方的成型性、吸湿性与溶解性均较好,优化得到的制粒工艺合理、可行.表6,参5.
To study Changjian tablets granulating process.Methods:By single factor method,Its moulding ability、solubility and anti Hygroscopicity as the indexes,filter out the types of prescription adding accessories,matching and the best processing conditions.Result:Determine the optimum processing conditions are dry extract powder ratio of 1:2 and accessories,With 85% ethanol prepared granules,the amount of 30% to 35%.Conclusion: The prescription moulding ability、solubility and antiHygroscopicity were better,Optimized molding technique is reasonable and feasible.6tabs.,5refs.
出处
《湖南环境生物职业技术学院学报》
CAS
2011年第1期24-27,共4页
JOurnal of Hunan Environment Biological Polytechnic
基金
湖南环境生物职业技术学院院长基金资助项目(编号:Z09-06)
关键词
肠健片
成型工艺
吸湿性
溶解性
Changjian tablets
granulating process
Hygroscopicity
Solvability