整体滋养汤治疗尿毒症血液透析患者营养不良38例临床研究

Observation of Zhengtiziyang decoction on malnutrition in hemodialysis patients

目的观察整体滋养汤治疗尿毒症血液透析(HD)患者营养不良的临床疗效。方法将76例尿毒症HD营养不良患者随机分为2组,对照组38例予常规充分HD维持治疗及高能量优质蛋白饮食治疗,治疗组38例在对照组治疗基础上予自拟整体滋养汤。2组均治疗20 d为1个疗程,2个疗程后观察2组临床症状改善情况,并对营养状况进行评估。结果 2组治疗后精神萎靡、纳少、腹胀及乏力改善率均高于对照组(P<0.05)。治疗组治疗后前白蛋白、白蛋白、转铁蛋白、总胆固醇及血红蛋白均较本组治疗前、对照组治疗后升高(P<0.05)。结论整体滋养汤可明显改善尿毒症HD患者营养不良状况。

Objective To observe the effect of Zhengtiziyang decoction on malnutrition in hemodialysis patients.Methods 76 cases of malnutrition in hemodialysis were randomly divided into two groups.38 patients in control group were treated by maintenance treatment of hemodialysis and high-energy high-protein diet.38 cases in treatment group were given combination of routine therapy and Zhengtiziyang decoction.The course was twenty days in two groups.The therapeutic effect was evaluated after two courses.Results The improvement rate including apathetic,poor appetite,bloating and fatigue after treatment was higher than that before treatment in two groups（P0.05）.The levels of albumin precursor,albumin,Tf,TC and hemoglobin after treatment in treatment group was higher than that before treatment and after treatment in control group（P0.05）.Conclusion Zhengtiziyang decoction can obvious improve malnutrition in hemodialysis patients.