262例药疹住院病例分析

Analysis of 262 Inpatients with Drug Eruption

目的：探讨药疹与某些致敏药物的联系。方法：查阅了１９９４年１月～１９９８年１１月我院药疹住院病历２６２例，对致敏药物的种类及疹型进行了统计分析。结果：怀疑致敏药物１０５种，其中抗生素１３８例，占５２．６７％；解热镇痛药５１例，占１９．４７％；其次为疫苗类和中药等。药疹的分型以荨麻疹型最多，占３６．２６％：其次为麻疹样和猩红热样型。结论：引发药疹最多的药物是抗生素．其次为解热镇痛药、疫苗类和中药。

AIM: To discuss the relation between drug eruption and some scnsitizing medieations. METHOD: The types ofdrug eruption and sensitizing medications were analyzed in 262 cases admitted between January 1994 and November 1998 whowere treated by 105 kinds of medications. RESULTS: Drug eruptions occured in 138(52. 67% ) and 51(19. 47% ) cases treatedby antimicrobial agents and antipyretic-analgesia respectively. Other dedications which could give rise drug eruption werevaccine and Chinese drugs. The most common eruption was urticaria type, then measles and scarlet type. CONCLUSION: Antimicrobial agents may cause more drug eruption than antipyretic-analgesia, vaccine and Chinese drugs.