紫杉醇抗癌机制研究进展

Advances in Study on M echanism of Antitum or Action by Taxol

总结近年来紫杉醇抗癌机制的研究进展，阐述其多种可能的作用机制，包括增加微管动力学的稳定性，促进肿瘤细胞凋亡，提高宿主细胞免疫性及诱导肿瘤坏死因子的产生等。作用机制的研究可为指导临床更好地应用该类药物提供依据。

Recent advances in study on m echanism of tum oricidal action by taxol w erereview ed,and som e possible m echanism s,such as stabilizing the m icrotubules dynam ics, pro m oting apoptosis oftarget cancer cells,activating m acrophage to enhance the im m unity of thehost and inducing biosynthesis of T N F αetc.,w ere described The study w ill play an im por tant role in guiding clinical use of taxol.