肾功能不全透析患者的弓形虫血清学调查

Serological investigation on Toxoplasma gondii infection in dialysis patients with renal insufficiency

选择肾功能不全的透析患者作为病例组,健康体检人员作为对照组,对其弓形虫特异性IgG抗体进行检测。共检测透析患者205例,弓形虫IgG阳性率为27.3%;对照组360人,IgG阳性率为3.6%,两者差异有统计学意义(P<0.05)。透析患者中有输血史者阳性率为31.2%,无输血史者阳性率为19.2%,两者差异有统计学意义(P<0.05)。肾功能不全透析患者的弓形虫感染率明显高于普通人群,是弓形虫感染的潜在危险因素。

A total of 205 dialysis patients with renal insufficiency were selected as an experiment group,and 360 healthy people were selected as a control group.The specific IgG antibodies of Toxoplasma gondii of the objects in the 2 groups were detected by ELISA.The positive rates of the experiment and control groups were 27.3% and 3.6%,respectively,with a significant difference between them（P0.05）.Among the dialysis patients with renal insufficiency,the positive rates of the patients with or without a history of blood transfusion were 31.2% and 19.2%,respectively,and there was a significant difference between them（P0.05）.In conclusion,the infection rate of T.gondii in dialysis patients with renal insufficiency is higher than that of common people,and dialysis and/or blood transfusion may be potential risk（s） for Toxoplasma gondii infection.