前列腺上皮肉瘤的PSAD与前列腺癌比较

COMPARING PSAD OF PROSTATIC INTRAEPITHELIAL NEOPLASIA WITH PROSTATIC CANCER.

本文报告经病理和免疫组化确诊的前列腺癌（PCa）57例，前列腺上皮肉瘤（PIN）54例和前列腺增生104例，比较各组的前列腺体积（PV），血清前列腺特异性抗原（PSA）和PSA密度（PSAD）。结果显示PIN与BPH的PSA、、PV和PSAD差异不明显（P＞0．05），但与PCa组差异显著（P＜0.01）。以PSA10ng／ml和PSAD0.2为界值，评价PCa组，其敏感性备为49％和42％，特异性79％和84％，准确性64％和63％。

prostate specific antigen (PSA) by means of radioimmuno assay, prostate specific antigen density(PSAD) and prostatic volume (PV) were assayed in 57 prostatic carcinoma patients (PCa). 54 prostate intraepithelial neoplasia(PIN) and 104 benign prostatic hyperplasia (BPH) as controls. It was significant difference between PCa and PIN and BPH (P<0. 01), but mild between PIN and BPH. At the upper limit of PSA 10ng/ml and PSAD 0. 2 for PCa, the specificity 79% and84%, and the accuracy 64% and 63% respectively.