应用肺灌注显像预测病人肺动脉压力

Evaluation of Pulmonary Artery Pressure by Lung Perfusion Scintigraphy

研究 Ｌ Ｓ法在预测病人肺动脉压力方面的功效。 方法：对２２ 例患者于术前行肺灌注显像研究，应用 Ｌ Ｓ法计算出肺动脉压力（ Ｐ Ａ Ｐ），并与病人心导管资料或术中测压资料做对比。 结果：计算出的 Ｐ Ａ Ｐ与测出的 Ｐ Ａ Ｐ呈明显相关（ｒ＝ ０．９２， Ｐ＝ ０００１），与病人心胸比率（ｒ＝ ０．７５， Ｐ＝ ０．０００１），肺细血管嵌压（ｒ＝ ０．９０， Ｐ＝ ０．０００９）和全肺阻力（ｒ＝０．８０， Ｐ＝ ０．０１）明显相关；该方法诊断肺动脉高压的敏感度和特异度均为 ９２％ ，阳性抑然比为１１．５，阴性抑然比为０．０８７。 结论： Ｌ Ｓ法可准确直接地预测病人肺动脉压力。

Objective:To evaluate the value of lung perfusion scintigraphy in estimation of pulmonary artery pressure in patients with various heart diseases.\ Methods: 99 mTc MAA lung perfusion scintigraphy was performed in 22 patients with various heart diseases. Patients were in lateral decubitus position. The pulmonary artery pressure(PAP) was calculated by LS method.\ Results:The calculated PAP, when comparison with hemodynamic parameters, correlated strongly with measured PAP( r= 0.92, P= 0001),pulmonary capillary wedge pressure( r= 0.90, P= 0.0009) and total pulmonary resistance index( r= 0.80, P= 0.01),respectively. The sensitivity and specificity of LS method for diagnosis of pulmonary hypertension were 92%. \ Conclusion:LS method of lung perfusion scintigraphy could estimate pulmonary artery pressure efficiently and directly. This method deserve to be further investigation.