子宫动脉栓塞治疗对子宫内膜功能影响的超声随访评估

Ultrasonographic evaluation of the effects of Uterine Arterial Embolization on endometrium function

目的观察子宫动脉栓塞(UAE)治疗子宫肌瘤对子宫内膜功能的影响及其持续时间。方法选择20～40岁因子宫肌瘤行UAE患者40例,经阴道彩色多普勒超声观察UAE前后子宫内膜的厚度、血流类型、血流个数及内膜下动脉RI、PI。结果 (1)平均内膜厚度和血流分型在UAE后6个月与UAE前比较有统计学差异(P<0.05),UAE 1年与UAE前比较无统计学差异(P>0.05)。内膜血流个数UAE前、后比较均无统计学差异(P>0.05)。(2)内膜下动脉PI在UAE 1年内与UAE前比较有统计学差异(P<0.05),内膜下动脉RI在UAE前后比较无统计学差异(P>0.05)。结论 UAE治疗1年内子宫内膜厚度及血流灌注会出现不完全和暂时的影响,UAE1年半后恢复正常。

Objective To study extent and duration of the influence of uterine arterial embolization （UAE） treat- ment on endometrium function in patients with leiomyoma. Methods Forty females with leiomyoma, aged from 20 to 40 years, were enrolled and treated with UAE. Endometrium thickness, blood flow type, blood flow number and the RI and PI of internal membrane artery were assessed by transvaginal color Doppler ultrasonography before and after UAE. Results （1） Significant differences in endometrium thickness and blood flow type were observed between 6 months after UAE and baseline （ P 〈 0. 05 ） ; while there was no significant difference revealed between baseline and 1 year after UAE. （2） Significant difference in internal membrane artery PI was revealed between baseline and 1 year after UAE （ P 〈 0. 05 ）, while no significant difference was revealed in internal membrane artery RI. Conclusion Temporary and reversible changes in endometrium thickness and uterine blood supplement are induced by UAE with a duration of less than 1.5 years.