摘要
目的探讨2型糖尿病合并冠心病患者糖化血红蛋白(HbA1C)、血清超敏C-反应蛋白(hs-CRP)及血浆D-二聚体(D-dimer)水平检测的临床价值。方法分别测定143例糖尿病(其中61例并发冠心病,82例无冠心病)患者HbA1C、hs-CRP、D-dimer水平,并与85例健康人作比较。结果 HbA1C、hs-CRP及D-dimer含量在健康对照、2型糖尿病患者以及合并冠心病患者组逐渐升高,差异有统计学意义(P<0.01,P<0.05),且在2型糖尿病及合并冠心病患者组中,三者呈正相关关系(P<0.05)。结论联合检测糖尿病患者HbA1C、hs-CRP和D-dimer水平的变化有利于观察病情,对评价疗效及预防冠心病等并发症具有重要的临床意义。
Objective To investigate the clinical value of hemoglobin A1c（HbA1C）,high sensitivity C-reactive protein（hs-CRP） and D-Dimer levels in type 2 diabetes mellitus（T2DM）patients with coronary heart disease.Methods HbA1C,hs-CRP and D-dimer levels were measured in T2DM patients with CHD（n=61）,T2DM patients without CHD（n=82） as well as 85 healthy people.Results The levels of HbA1C,hs-CRP and D-Dimer gradually increased in healthy control group,T2DM patient group and T2DM with CHD patient group（P〈0.01,P〈0.05）,and there were positive relations among HbA1C,hs-CRP and D-dimer in T2DM and T2DM with CHD patient groups（P〈0.05）.Conclusion Integrated detection of HbA1C,hs-CRP and D-dimer levels are associated with T2DM patients with coronary heart disease.Monitoring those levels might be helpful for the surveillance and outcome prediction.
出处
《检验医学与临床》
CAS
2011年第9期1073-1074,共2页
Laboratory Medicine and Clinic
