期刊文献+

非小细胞肺癌和食管癌微血管密度的检测意义 被引量:2

The Detective Significance of Microvascular Density in Non-Small-Cell Lung Cancer and Esophageal Carcinoma
下载PDF
导出
摘要 目的探讨微血管密度(MVD)在判断非小细胞肺癌及食管癌患者预后方面的价值。方法入组手术治疗的34例非小细胞肺癌和81例食管癌患者,用免疫组化法检测肿瘤标本的MVD,分析检测结果与预后的关系。结果非小细胞肺癌MVD只对总生存期有独立预测意义;食管癌MVD对术后无病生存期及总生存期均具有独立预测意义。结论 MVD是非小细胞肺癌和食管癌的独立预后因子。 Objective To study the predictive value of microvascular density(MVD) in determining the prognoses of non-small-cell lung cancer and esophageal carcinoma.Methods This study included 34 patients with non-small-cell lung cancer and 81 patients with esophageal carcinoma.MVD was detected using immunohistochemical methods in order to find the correlation between MVD and prognosis of the patients.Results Of the patients with non-small-cell lung cancer,MVD was an independent predicator for overall survival time.Of the patients with esophageal carcinoma,MVD was an independent predicator for disease free survival time and overall survival time.Conclusion MVD may be an independent predicator for non-small-cell lung cancer and esophageal carcinoma.
机构地区 苍山县人民医院
出处 《肿瘤基础与临床》 2011年第2期109-111,共3页 journal of basic and clinical oncology
关键词 非小细胞肺癌 食管癌 微血管密度 预后 non-small-cell lung cancer esophageal carcinoma microvascular density prognosis
  • 相关文献

参考文献5

  • 1Weidner N.FoLkman J.Pozza F,et al.Tumor angiogenesis:a new significant and independent prognostic indicator in early-stage breast carcinoma[J].J Natl Cancer Inst,1992,84(24):1875 -1887.
  • 2van der Zee R,Murohara T,Luo Z,et al.Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium[J].Circulation,1997,95 (4):1030-1037.
  • 3Gospodarowicz D,Ferrara N,Schweigerer L,et al.Structural characterization and biological functions of fibroblast growth factor[J].Endocr Rev,1987,8(2):95-114.
  • 4Barbareschi M,Gasparini G,Morelli L,et al.Novel methods for the determination of the angiogenic activity of human tumors[J].Breast Cancer Res Treat,1995,36(2):181 -192.
  • 5Schlingemann RO,Rietveld FJ,Kwaspen F,et al.Differential expression of markers for endothelial cells,pericytes,and basal lamina in the microvasculature of tumors and granulation tissue[J].Am J Pathol,1991.138(6):1335-1347.

同被引文献12

引证文献2

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部