EB病毒与逆行性牙髓炎的相关性研究

Investigation on the association between Epstein-Barr virus and retrograde pulpitis

目的研究EB病毒(EBV)与逆行性牙髓炎的相关性。方法应用巢式聚合酶链反应(nPCR)技术,检测30例逆行性牙髓炎患者和30例健康对照者牙髓组织中的EBV,比较分析它们的检出率。结果 30例逆行性牙髓炎患者的EBV检出率为36.67%,显著高于健康对照者(0%),差异有统计学意义(P<0.01)。结论提示EBV与逆行性牙髓炎有相关性。

Objective To investigate the relationship between Epstein-Barr virus（EBV） and retrograde pulpitis. Methods Pulp tissue samples were collected from 30 patients of retrograde pulpitis and 30 healthy subjects. The nested polymerase chain reaction （nPCR） was used to examine EBV in pulp tissue. Results The positive rate of EBV detected in samples which were collected from the patients with retrograde pulpitis was significantly higher percentages （36.67%） compared with that from healthy pulp controls （0%, P 0.01）. Conclusions EBV may be related to retrograde pulpitis.