无创机械通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的疗效分析

Effect analysis of BiPAP in the treatment of COPD combined Ⅱ type of respiratory failure

目的:探讨应用面罩双水平气道正气通气(BiPAP)治疗慢性阻塞性肺疾病(COPD)急性加重合并Ⅱ型呼吸衰竭的临床效果。方法:将COPD合并Ⅱ型呼吸衰竭患者60例,随机分为两组,治疗组30例,对照组30例,对照组给予常规治疗,治疗组在对照组的基础上进行面罩双水平气道正压无创通气治疗,观察两组患者治疗前后动脉血气及呼吸频率、心率变化、住院时间、气管插管率、呼吸衰竭纠正时间变化情况。结果:治疗组pH值、PaO2、PaCO2较治疗前明显改善(P<0.05),与对照组比较,差异有统计学意义(P<0.05);呼吸频率、心率改变与对照组比较,差异有统计学意义(P<0.05);治疗组住院时间、呼吸衰竭纠正时间较对照组明显缩短,治疗组改气管插管通气率低于对照组,两组比较差异有统计学意义(P<0.05)。结论:BiPAP治疗COPD合并Ⅱ型呼吸衰竭效果满意,操作简单,可作一线治疗手段。

Objective：To explore application BiPAP treatment of COPD combined Ⅱ type of respiratory failure.Methods：Patients with COPD combined Ⅱ type of respiratory failure 60 cases randomly divided into two groups,treatment group were 30 cases and control group were 30 cases,control group was gaven routine treatment.The treatment group applicated control group therapy applied BiPAP add with treatment.Observed both groups of patients before and after the treatment of arterial blood gas and breathing,heart rate changes,the length of time,tracheal intubation rate,respiratory failure correct time change.Results：In Treatment group,the pH value,PaO2,PaCO2 significantly improved（P0.05）,the difference was statistically significant compared with control group（P0.05）;the difference of respiratory rate,heart rate changes were statistically better compared with control group（P0.05）;Hospital stay,respiratory failure to correct time were shorter and ventilation rate of intubation was lower than control group.The difference was statistically significant（P0.05）.Conclusion：The effect of BiPAP treating COPD with typeⅡrespiratory failure is satisfactory,it can be used as first-line treatment.