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洛伐他汀治疗高脂血症182例

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摘要 目的探讨不同剂量的洛伐他汀治疗高脂血症的临床疗效及其安全性。方法将我院2008年3月至2010年3月所收治的182例高脂血症患者随机分成观察组100例和对照组82例,观察组给予洛伐他汀40mg/d,对照组给予洛伐他汀20mg/d。结果观察组和对照组治疗4周及12周后,TC、LDL-C水平均较治疗前显著降低(P<0.01)。观察组降低TC及LDL-C的作用明显优于对照组(P<0.05),差异有统计学意义。2组均未出现其他不良反应。结论洛伐他汀的降脂效果与临床用药剂量有明确的正相关性,较大剂量的洛伐他汀治疗低密度脂蛋白升高的患者具有显著的临床疗效和良好的安全性。
作者 周德春
机构地区 茶陵县人民医院
出处 《中外医疗》 2011年第10期104-104,106,共2页 China & Foreign Medical Treatment
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