妇产科围术期预防性应用抗生素200例临床观察

The clinical observation of prophylactic application of antibiotic at intraoperative period in department of obstetrics and gynecology:on 200 cases report

目的探讨剖宫产围术期预防性应用抗生素不同用药方法预防术后感染的效果。方法将该院200例妇产科手术患者随机分试验组和对照组,各100例。试验组于术前30min给予二联抗生素单次预防性静脉滴注,对照组按常规方法于手术后对产妇给予二联抗生素静脉滴注3～7d。分析比较2组术后治愈率、最高体温、退热时间和术后住院天数及腹部切口感染情况。结果 2组术后治愈率均为100%。试验组术后退热时间为(39±8)h快于对照组的(63±12)h,差异有统计学意义(P<0.05);且试验组术后住院天数为(4.31±1.56)d明显少于对照组的(7.32±3.23)d,差异有统计学意义(P<0.05);试验组术后切口感染率为3%少于对照组的7%,差异有统计学意义(P<0.05)。结论妇产科围术期预防性应用抗生素是预防剖宫产术后感染安全、有效的较好方法。

Objective To discuss the effect of prevent infection of prophylactic application of antibiotic with different treatment method in cesarean section perioperative.Methods 200 cases patients were divided into experimental group and control group,each of 100 cases.Before operation 30min,experimental group were given single bivalent prophylactic intravenous antibiotics;According to conventional methods,after surgery control group given two kinds antibiotics,intravenous 3～7d.Compared the cure rate,the highest temperature,pyretolysis time,postoperative hospitalization days and situation of wound infection of two groups.Results The cure rate of 2 groups was 100%.The pyretolysis time of experimental group[（39±8） h] was faster than that of control group[（63±12） h],the difference was statistically significant（P0.05）;The postoperative hospitalization days[（4.31±1.56） d] was significantly less than control group[（7.32±3.23） d],the difference was statistically significant（P0.05）;The wound infection rate of experimental group（3%） was less than that of control group（7%） ,there had significant difference（P0.05） .Conclusion Prophylactic application of antibiotic in intraoperative period is safe,effective in cesarean section.