甲型H1N1流感患者白细胞分类的临床观察

Clinical Observation of White Blood Cell Typing in HIN1 Influenza Patients

目的 通过甲型H1N1流感患者白细胞分类的变化分析,并与健康人群比较,探讨白细胞分类在甲型H1N1流感临床诊断或筛检中的应用价值.方法 对经PCR核酸检测确诊的甲型H1N1流感患者采静脉血用sysmex XE-2100五分类血细胞分析仪做白细胞分类,并经统计学处理.结果 甲型H1N1流感患者白细胞分类与正常人群相比较,其中白细胞（WBC）,中性粒细胞（NEUT）及嗜碱性粒细胞（BASO）差异均无统计学显著性意义（P＞0.05）.淋巴细胞（LYMPH）、单核细胞（MONO）和嗜酸性粒细胞（EO）差异有统计学显著性意义（P＜0.01）.结论 白细胞分类中单核细胞比例和计数的增高对甲型H1N1流感的临床诊断具有一定的指导意义,可以作为甲型H1N1流感早期诊断或筛检的参考指标.

Objective To probe the value of white blood cell typing in H1N1 clinical diagnosis or screening. Compared with healthy population. Methods Analyze the venous blood of H1N1 patients diagnosed by PCR nucleic acid detection,typing the white blood ceil through analysator, and then with statistical treatment. Results Compared with healthy adults,HiN1 patients was no significant difference in WBC,NEUT and BASO （P〉0.05）. There was significant difference in LYMPH, MONO and EO（P〈0. 01）. Conclusion White blood cell typing,especially the increasing of mononuclear cells,had some significance for the clinical diagnosis of H1N1 patients. So white blood cell typing could be regarded as reference indices for the early H1N1 patients.