季节对血压、血脂的影响

The impact of season for blood pressure and blood lipid

目的探讨不同季节变化对人体血压、血脂的影响。方法分析我院2008年全年健康体检人员体检资料,按月份分为四个季节,比较其血压、血脂的变化。结果人体血压、总胆固醇﹑高密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平在不同季节成周期性变化。收缩压平均水平在冬季明显高于夏季,相差9.31mmHg;总胆固醇和低密度脂蛋白胆固醇平均水平在冬季明显高于夏季,冬季分别为4.80mmol/L和2.65mmol/L,夏季分别为4.62mmol/L和2.39mmol/L,差值分别为0.18mmol/L(4%)和0.26mmol/L(6%)(P<0.05);高密度脂蛋白胆固醇平均水平则相反,冬季为1.44mmol/L,夏季为1.52mmol/L,差值为0.08mmol/L(5%)(P<0.01)。结论在寒冷的冬季,对血压、血脂轻度增高的诊断应充分考虑季节因素,对患者应加强血压及血脂的监测和适当调整药物的剂量。

Objective To investigate the influence of different seasons for blood pressure and lipids.Methods The people accepted health examination in our hospital in 2008 were enrolled.The data of blood pressure and lipids was compared between summer and winter.Results The levels of blood pressure,cholesterol,high density lipoprotein（HDL） and low-density lipoprotein（LDL） were changed periodically in different seasons.The mean level of systolic pressure in winter was significantly higher by 9.31 mm Hg than that in summer.And the level of cholesterol and LDL in winter increased by 0.18 mmol/L（4%） and 0.26 mmol/L（6%） respectively in average as compared with that in summer（P 〈0.05）.However,in winter,the average level of HDL（1.44 mmol/L） was lower by 0.08 mmol/L（5%） than that in summer（P 〈0.01）.Conclusion The season factor must be taken into account in the diagnosis of mild increase of blood pressure and lipids in winter.So patients should receive intensive lipid lowering and aggressive blood pressure lowering therapy.