胃癌患者69例预后影响因素分析

Multivariate prognostic analysis of 69 cases with gastric carcinoma after operation

目的探讨影响胃癌预后的相关危险因素。方法回顾性分析69例胃癌行手术治疗患者的临床资料，并进行单因素和COX多元回归分析。结果单因素及多因素分析显示，胃癌病理学分级、肿瘤TNM分期、淋巴结转移因素与胃癌手术预后存在相关性，是影响胃癌预后的独立相关危险因素（均P〈0．05）。而性别、年龄、根治方式、术后辅助化疗等因素与胃癌预后无关（均P〉0．05）。结论影响胃癌患者预后的原因是多方面的，肿瘤TNM分期是其主要危险因素。

Objective To investigate the relevant, factors of postoperative treatment effect of gastric carcinoma. Methods 69 patients with gastric carcinoma were chosen. The clinical data of all patients were analyzed with multiple regression analysis. Results There was a correlation between histological grades, TNM stage, lymph node metastasis and postoperative prognosis of gastric carcinoma（ all P 〈 0. 05 ）. There was no correlation between sex, age, the method of radical operation, adjuvant chemotherapy after radical surgery and postoperative prognosis of gastric carcinoma （ all P 〉 0.05 ）. Conclusion The prognosis of the operation of stomach cancer had many influencing factors, and TNM stage of the tumor was the main risk factor.