摘要
目的:分析年轻与中老年女性乳腺癌病理特征差异。方法:回顾分析我院2002年1月~2010年8月收治的64例年龄35岁的年轻乳腺癌患者的临床及病理资料,并与同期所有收治的35岁以上的291例中老年女性乳腺癌进行比较,所有病例均经手术治疗及病理确诊。结果:年轻组占同期收治病例的18.03%;年轻组雌激素受体(ER)或孕激素受体(PR)阳性患者比例低于中老年组差异有统计学意义(P〈0.05);年轻组无淋巴结转移及ER阴性患者比例高于中老年组差异有统计学意义(P〈0.05);两组乳腺癌患者中病理组织类型、肿瘤大小、pTNM分期比较,差异均无统计学意义。结论:ER表达、PR表达、淋巴结未转移伴ER阴性的患者年轻组与老年组比较差异有统计学意义(P〈0.05);年轻女性乳腺癌发病率呈上升趋势,一般认为较年老乳腺癌相比更具侵袭性,预后差。本研究数据显示年轻组占同期收治病例的18.03%,需要提高我区年轻女性对乳腺癌的警惕,加强对乳腺癌知识的宣传教育。
Objective:To analyze the differences of the clinlcopathologic features of breast cancer in young and middle-aged womenMethods: A retrospective study compared the clinical and pathlolgical data of 64 cases of young women(≤35 years)with breast cancer with 291 cases of middle-aged women(35 years)with breast cancer treatde an our hospital from January 2002 to August 2010 All these cases had undergone surgical treatment and been confirmed by pathologist. Results: The young patients(≤35 years)accounted for 18.03% of the diagnosed cases of breast cancer.The proportion of estrogen receptor(ER)or progesterone rerceptor(PR)positive patients in young group was lower than the middle-aged group(P0.05),The proportion of young patients with non-lymphatic metastasis and ER negative was higher than the middle-aged patients (P0.05),There were no statistically significant differences between two groups in the pathological types.tumour size and pTNM classification Conclusion: There were statistically significant differences in ER or PR positive and ER negative with non-lymphatic metastasis between young women(≤35 years) showed an increasing tendency.It is generally considered that young patients with breast cancer have more aggressive and poorer prognosis than the middle-agde patients.Our data showed the young patients(≤35 years) account for 18.03% of the diagnosed cases.which indicated that young women should increase awareness of breast cancer in our region and strengthen the propaganda education of breast cancer.
出处
《内蒙古医学杂志》
2011年第3期294-297,共4页
Inner Mongolia Medical Journal
基金
内蒙古自治区肿瘤防治与分子机制研究创新团队专项基金(2009)
关键词
乳腺癌
年轻女性
病理特点
Breast cancer
Young women
Pathological features