宫颈癌MRI分期与病理对照研究

Correlative study between MR imaging and pathology in cervical cancer staging

目的探讨宫颈癌磁共振成像(MRI)分期与病理分期的相关性。方法 80例经手术或活检病理证实的宫颈癌患者行盆腔MRI检查,MRI的成像序列包括T1加权像、T2加权像、脂肪抑制T2加权像、弥散加权成像,以及钆喷酸葡胺增强T1加权像。观察肿瘤的位置、信号特征及侵犯范围。将MRI所见与病理结果相对比。结果 MRI对宫颈癌分期总的准确率为88.73%。对宫旁侵犯判断的准确率为92.50%,特异度为91.18%,敏感度为100%。MRI与病理诊断的差异主要与宫旁浸润的评价差异有关。结论 MRI在宫颈癌临床分期中具有很高的准确性,是宫颈癌诊断中重要的影像学手段。

Objective To study the correlation between MR imaging and pathologic findings in the staging of uterine cervical carcinoma.Methods Pelvic MR imaging was performed in 80 patients with cervical carcinoma proved by pathology or biopsy.The MRI scan sequences included axial SE T1 weighted image（T1WI）,axial and sagittal TSE T2 weighted image（T2WI）,coronal fat saturation TSE T2WI,diffusion weighted sequence,and axial,sagittal,and coronal Gd-DTPA enhanced SE T1WI.MR images were analyzed for the location,signal characteristics,and extension of the primary tumor.MR imaging findings were compared with surgical-pathologic results.Results According to the pathologic findings,the accuracy of MR imaging in staging was 88.73%.The accuracy,specificity,and sensitivity for parametrial extension were 92.50%,91.18%,and 100%,respectively.The diagnosis difference between MRI and pathological examination was mainly by the evaluation difference of parametrial invasion.Conclusion MRI has a high accuracy in the clinical staging of cervical cancer,and is an important imaging modality in cervical cancer diagnosis.