期刊文献+

线虫cystatin对宿主免疫反应的调控 被引量:1

原文传递
导出
摘要 寄生性线虫一般于宿主的消化道或组织内寄生,经常暴露于复杂的宿主免疫系统中而受到持续的免疫攻击但依然可存活数年。分泌免疫调节因子,进而阻断宿主免疫反应、细胞因子网络及信号通路是线虫抵御宿主免疫反应的有效手段之一。半胱氨酸蛋白酶抑制剂(cystatin)就是线虫分泌的重要免疫调控因子之一。本文就近年来线虫cystatin调节宿主免疫反应的研究进行综述。
出处 《热带医学杂志》 CAS 2011年第2期232-235,共4页 Journal of Tropical Medicine
基金 国家"973"项目(2010CB530004)
  • 相关文献

参考文献53

  • 1Nicklin MJ,Barrett AJ.Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatin [J]. Biochem J, 1984, 223( 1 ) :245-253.
  • 2Henskens YM,Veerman EC,Nieuw Amerongen AV.Cystatins in health and disease[J]. Biol Chem Hoppe Seyler, 1996,377 (2): 71-86.
  • 3Barrett AJ.The cystatins : a diverse superfamily of cysteine peptidase inhibitors[J]. Biomed Biochim Acta, 1986,45(11-12) : 1363-1374.
  • 4Zucker-Franklin D, Warfel A, Grusky G, et al.Novel monocyte-like properties of microglial/astroglial cells.Constitutive secretion of lysozyme and cystatin-C [J]. Lab Invest, 1987,57(2) : 176-185.
  • 5Chapman HA Jr.Role of enzyme receptors and inhibitors in regulating proteolytic activities of macrophages[J]. Ann N Y Acad Sci, 1991,624 : 87-96.
  • 6Leung-Tack J, Tavera C, Er-Raki A, et al.Rat cystatin C : inhibitor of granulocyte phagocytic functions [J ]. Biol Chem Hoppe Seyler, 1990,371 (Suppl) : 255 -258.
  • 7Leung-Tack J,Tavera C,Gensac MC,et al.Modulation of phagocytosis-associated respiratory burst by human cystatin C: role of the N-terminal tetrapeptide Lys-Pro-Pro-Arg [J]. Exp Cell Res, 1990, 188( 1 ) : 16-22.
  • 8Pierre P, Mellman I. Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells [J]. Cell, 1998,93(7) : 1135-1145.
  • 9Cappello F,Gatti E,Camossetto V,et al.Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting [ J ]. Exp Cell Res, 2004,297 ( 2 ) : 607- 618.
  • 10Isemura S,Saitoh E,Sanada K,et al.Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S[J]. J Biochem, 1991,110(4) :648-654.

同被引文献10

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部